Erectile Dysfunction Creams

Vitaros Cream vs Viagra: A Real User’s Guide to ED Treatments That Actually Work

Let’s talk about something a lot of men go through, but almost nobody talks about: erectile dysfunction. I’ve been there—and if you’re reading this, chances are you have too.

I remember the first time it happened. I was in my early 40s, healthy, and had no clue why I couldn’t stay hard. I thought it was just a one-off, but it happened again… and again. It crushed my confidence and started to affect my relationship.

I tried Viagra, then Cialis. They kind of worked, but I hated the side effects—headaches, flushed face, weird backaches. Plus, the wait time? Awkward. I wanted something that felt less clinical and more natural.

Enter Vitaros Cream. I’d never heard of it until a compounding pharmacist at Dillions Pharmacy explained how it works. I gave it a try—and let’s just say, I haven’t looked back.

This article is for guys like me who want the real comparison. Not just the science (though we’ll include that), but what it actually feels like to use these treatments. All compounded alprostadil cream formulations are made to exacting USP standards and reviewed by licensed U.S. providers.

Reviewed by: Dr. Karen M. Lopez, PharmD – Board-Certified Clinical Pharmacist specializing in men’s health at Dillions Pharmacy.

What Is Vitaros Cream?

Vitaros Cream is a topical erectile dysfunction treatment. It contains alprostadil, a vasodilator that increases blood flow by relaxing blood vessels. Unlike Viagra or Cialis, it’s applied directly to the urethral opening at the tip of the penis.

It starts working within 5 to 30 minutes and doesn’t require sexual arousal to be effective—unlike PDE5 inhibitors like Viagra.

Source: NIH – Alprostadil Clinical Research

What Is Viagra?

Viagra (sildenafil) is the most well-known oral medication for ED. It works by increasing blood flow through a different mechanism—by inhibiting the PDE5 enzyme. You take it 30–60 minutes before sex, and it only works if you’re sexually aroused.

While it’s effective, it comes with systemic side effects, timing constraints, and isn’t suitable for everyone—especially those with certain heart conditions.

Vitaros Cream vs Viagra: Side-by-Side Comparison

FeatureVitaros CreamViagra (Sildenafil)
Delivery MethodTopical (penile urethra)Oral tablet
Time to Work5–30 minutes30–60 minutes
Requires Arousal?NoYes
Duration of Effect~1 hour4–6 hours
Common Side EffectsMild burning, tinglingHeadache, flushing, nausea
Systemic EffectsMinimalModerate
Alcohol InteractionMinimalCan reduce effectiveness
Works for Heart Patients?Yes (under guidance)Often not safe
Availability in USACompounded version availableWidely available
Prescription Needed?YesYes

“Vitaros didn’t give me the same side effects. No headache, no stuffy nose. Just results—quick and clean.” — Peter, 47

Vitaros vs Cialis: Longer-Lasting vs Fast & Focused

Cialis (tadalafil) lasts much longer—up to 36 hours. That sounds ideal for flexibility, but for many men, it comes with lingering side effects and performance timing anxiety. These alprostadil injections are highly effective but often considered a last resort due to invasiveness and discomfort.”

FeatureVitaros CreamCialis (Tadalafil)
Onset Time5–30 minutes30–120 minutes
Duration~1 hourUp to 36 hours
Systemic Side EffectsMinimalHeadaches, muscle aches
Planning Needed?LessMore
Used Daily or As-Needed?As neededDaily or as needed

Vitaros vs Alprostadil Injections

Both Vitaros and penile injections contain alprostadil, but they differ in delivery.

FeatureVitaros CreamAlprostadil Injection
Application MethodUrethral creamPenile injection
Onset Time5–30 minutes5–20 minutes
InvasivenessLowHigh
Pain PotentialMild warmth/tinglingRisk of injection site pain
Prescription Required?YesYes

These injections are highly effective but often considered a last resort due to invasiveness and discomfort. Not sure if Vitaros is right for you? Explore our Viagra alternatives to see what other safe, effective options are available.”

Vitaros Cream vs Vacuum Devices

Vacuum erection devices (VEDs) are drug-free alternatives that use mechanical suction.

FeatureVitaros CreamVacuum Devices
MechanismTopical medicationPhysical suction
Ease of UseEasyModerate to difficult
Privacy/DiscretionHighLow
SpontaneityModerateLow
Risk of BruisingLowModerate

Who Should Consider Vitaros?

You may benefit from Vitaros if:

  • You experience side effects from oral ED medications
  • You have heart conditions or contraindications to PDE5 inhibitors
  • You want a fast-acting, localized option that doesn’t require arousal

“It took trial and error, but Vitaros gave me back confidence—and a sense of control.” — Mark, 53

Expert Guidance from Dillions Pharmacy

At Dillions, we don’t just offer prescriptions—we offer personalized care, safety-first consultations, and professional compounding services. All compounded alprostadil creams are made to exacting USP standards and reviewed by licensed U.S. providers.

We’ve helped thousands of men navigate their options with:

  • U.S.-licensed pharmacists
  • LegitScript-verified operations
  • Confidential, HIPAA-compliant consultations

Final Word: Vitaros Cream vs Viagra and Other Options

When it comes to treating ED, the goal isn’t just function—it’s confidence, safety, and quality of life.

Vitaros Cream may not be the most talked-about treatment in the U.S., but it’s a proven, effective, and safe alternative—especially when Viagra or Cialis cause unwanted side effects.

Don’t let hesitation hold you back. Explore what works for you—with support from experienced pharmacists who care.

Ready to take the next step?

Start your consultation with Dillions Pharmacy and discover the ED treatment that works for your body and your life.

Disclaimer: This article has been medically reviewed and is provided for informational purposes only. Always consult with a licensed healthcare provider before beginning any new treatment.

2 thoughts on “Vitaros Cream vs Viagra: A Real User’s Guide to ED Treatments That Actually Work

Leave a Reply

Your email address will not be published. Required fields are marked *